IMPORTANT INFORMATION
General Knowledge
When smoked, the average dose of DMT is believed to be somewhere between 30 to 150 milligrams (mg), and the onset of action can be felt almost instantly. The effects peak and plateau for 3 to 5 minutes, and gradually drop off with the duration of effect totaling 30 to 45 minutes.
DMT is structurally related to the neurotransmitter serotonin and, because of this, a condition called serotonin syndrome is a potentially lethal health risk associated with its use. Individuals taking antidepressants are at highest risk for this complication.
Due to limited research data, DMT is not known to cause physical dependence or addiction, although frequent recreational users may develop psychological cravings for the drug. The National Institute on Drug Abuse (NIDA) suggests that, unlike other hallucinogens, DMT use does not seem to induce tolerance of the drug.
Resources Medical News Today
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